Review Articles

The pharmacological management of obesity

André Marais
South African Family Practice | Vol 58, No 4 : July/August| a4510 | DOI: https://doi.org/10.4102/safp.v58i4.4510 | © 2016 André Marais | This work is licensed under CC Attribution 4.0
Submitted: 13 June 2016 | Published: 04 August 2016

About the author(s)

André Marais, Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Pretoria, South Africa

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Abstract

Obesity is a growing phenomenon and a global concern. It is well-known that it plays a significant role in the development of several preventable diseases. The physiological mechanisms in regulating energy intake and expenditure are complex and remain a target area for current and future research. The absence of a golden standard in determining the body’s composition provides for various measurement techniques, each with its own advantages and disadvantages. Lifestyle changes and reduced caloric intake form the backbone of any pharmacological intervention. A myriad of therapeutic agents are available which offer the provision for individualised treatment.

Keywords

anti-obesity agents; appetite; body composition; obesity; weight loss

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