Review Articles

The use of angiotensin-converting enzyme inhibitors in general medicine

M L I Mashitisho
South African Family Practice | Vol 54, No 4 : July/August| a1815 | DOI: https://doi.org/10.4102/safp.v54i4.1815 | ©
Submitted: 16 June 2011 | Published: 25 April 2012

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M L I Mashitisho, University of Limpopo(Medunsa Campus), South Africa

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Abstract

Angiotensin-converting enzyme (ACE) inhibitors are a class of drugs commonly used in the management of hypertension, congestive heart failure, cerebrovascular disease, stable coronary heart disease and diabetes-associated nephropathy. ACE inhibitors are divided into three classes, namely sulphydryl-containing ACE inhibitors structurally related to captopril, carboxyl-containing ACE inhibitors structurally related to enalapril, and phosphorus-containing ACE inhibitors structurally related to fosinopril. Though these classes of drugs are important in the treatment of the above conditions, they are not without side-effects. It is very important for clinicians to be aware of these side-effects so that patients can be warned, and compliance can be improved.

Keywords

Angiotensin Converting Enzyme Inhibitors

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