Die Rol van matige Wynverbruik tydens Maaltye in die Voorkoming van Hartsiektes

Abstract

Epidemiological evidence consistently link moderate red wine consumption with reduced incidence of cardiovascular disease. lt has been found that there is a much lower mortality from cardiovascular disease, mainly coronary artery disease (CAD), in the countries bordering the Mediterranean compared with that in Northern Europe. This was coined "The French Paradox", describing the phenomenon that the French have a low incidence of CAD despite the fact that they follow a diet rich in saturated fat. lt is well known that the French regularly consume red wine with their meals. Platelet aggregability plays an important role in the pathogenesis of CAD. Various phytochemicals in red wine may reduce platelet aggregation, serum lipid peroxidation and hence thrombosis. We investigated the effects of regular moderate red wine consumption on platelet aggregability ex vivo and on the serum lipid profile and antioxidant status.