Review Articles
Review of the safety of nonsteroidal anti-inflammatory drugs and selective cyclo-oxygenase-2 inhibitors
South African Family Practice | Vol 57, No 3 : May/June| a4285 |
DOI: https://doi.org/10.4102/safp.v57i3.4285
| ©
Submitted: 06 May 2015 | Published: 01 May 2015
Submitted: 06 May 2015 | Published: 01 May 2015
About the author(s)
G. S. Tarr, Winelands Rheumatology Centre, Stellenbosch, South Africa; and Helderberg Hospital Rheumatology Clinic, Somerset West, South AfricaHelmuth Reuter, Winelands Rheumatology Centre, Stellenbosch, South Africa; and Helderberg Hospital Rheumatology Clinic, Somerset West, South Africa; and Division of Rheumatology, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa
Full Text:
PDF (63KB)Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most common classes of medication used worldwide, and as the ageing population increases, the prevalence of painful arthritic conditions parallels this, resulting in the increased use of NSAIDs. Selective and nonselective cyclo-oxygenase inhibitors should be avoided, or at best used for short periods at the lowest possible effective dose, in patients with underlying artherosclerotic coronary disease.
Keywords
nonsteroidal anti-inflammatory drugs; NSAIDs; COX-2 inhibitors
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