Multi-drug-resistant tuberculosis (MDR-TB): Current situation in South Africa

Gboyega A Ogunbanjo
South African Family Practice | Vol 59, No 2 : March/April| a4679 | DOI: https://doi.org/10.4102/safp.v59i2.4679 | ©
Submitted: 01 May 2017 | Published:

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Gboyega A Ogunbanjo, Editor-in-chief South African Family Practice Journal, South Africa

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Multi-drug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection which is resistant to treatment with at least two of the most powerful first-line anti-TB drugs, namely isoniazid and rifampicin. Globally, MDR-TB caused an estimated 480 000 new TB cases and 250 000 deaths in 2015 and accounted for 3.3% of all new TB cases worldwide.1 MDR-TB, or rifampicin-resistant TB, causes 3.9% of new TB cases and 21% of previously treated TB cases, and most MDR-TB cases occur in South America, southern Africa, India, China, and the former Soviet Union.1


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