Anaphylaxis and anaesthesia

  • Bojan Korda University of the Witwatersrand
Keywords: anaesthesia, anaphylaxis


Anaphylaxis is defined as ‘a severe life-threatening, generalised or systemic hypersensitivity reaction’.1 The recent 6th National Audit Project (NAP6) in the United Kingdom (UK) defined perioperative anaphylaxis as ‘anaphylaxis which occurs in patients undergoing a procedure requiring general or regional anaesthesia or sedation or managed anaesthesia care (anaesthesia monitoring only) under the care of an anaesthetist between the period of first administration of a drug (including premedication) and the post-procedure transfer to a ward, or critical care’.2 This short narrative review will discuss the recent NAP6 results in the context of current knowledge, as relevant to the South African anaesthetist.

Author Biography

Bojan Korda, University of the Witwatersrand
Department of Anaesthesia Chris Hani Baragwanath Academic Hospital University of the Witwatersrand
Refresher Course