Case studies

Fatal angioedema induced by angiotensin conversion enzyme (ACE) inhibitors

Marianne Tiemensma, Elsie H. Burger, Jacob J. Dempers, Shabbir A. Wadee
South African Family Practice | Vol 52, No 3 : May/June| a1321 | DOI: https://doi.org/10.1080/20786204.2010.10873974 | ©
Submitted: 09 February 2009 | Published: 30 June 2010

About the author(s)

Marianne Tiemensma, Stellenbosch University, South Africa
Elsie H. Burger, Stellenbosch University, South Africa
Jacob J. Dempers, Stellenbosch University, South Africa
Shabbir A. Wadee, Stellenbosch University, South Africa

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Abstract

ACE inhibitors are often prescribed in the treatment of hypertension, heart failure and kidney disease. These drugs are on the Essential Drugs List, and are therefore used at primary to tertiary health care levels in South Africa. Angioedema is considered a rare, but potentially fatal side-effect of this agent, with a reported incidence of 0.1–0.2% worldwide.1 Its incidence in the South African population is, however, unknown.

Keywords

unnatural deaths; ACE-inhibitors; angioedema; side-effect; hypertension

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