CPD Articles

An introduction to insulin use in type 2 diabetes mellitus

Ankia Coetzee
South African Family Practice | Vol 65, No 1 : Part 2| a5702 | DOI: https://doi.org/10.4102/safp.v65i1.5702 | © 2023 Ankia Coetzee | This work is licensed under CC Attribution 4.0
Submitted: 29 December 2022 | Published: 20 April 2023

About the author(s)

Ankia Coetzee, Department of Medicine, Division of Endocrinology, Tygerberg Academic Hospital, Cape Town, South Africa; and, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa


The benefits of the newer antidiabetic agents available for managing type 2 diabetes mellitus (T2DM) remain indisputable, but many patients will require insulin therapy in the disease course. Given the limited access to newer antidiabetic agents, insulin remains a standard treatment modality in T2DM in South Africa. Early, multifactorial intervention remains ideal, but glucose, blood pressure and cholesterol values remain above target in many countries. Barriers to achieving glucose control in South Africa include the healthcare provider’s being unfamiliar with the practicalities of insulin administration, initiation and titration. This article highlights these gaps and offers pragmatic solutions to overcome them.


insulin; type 2 diabetes; practical; multifactorial; basal


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