Original Research

Factors influencing adherence to antiretroviral therapy among young adults in Limpopo province

Victoria Mashele, Gert J.O. Marincowitz, Clara Marincowitz
South African Family Practice | Vol 66, No 1 : Part 3| a5973 | DOI: https://doi.org/10.4102/safp.v66i1.5973 | © 2024 Victoria Mashele, Gert J.O. Marincowitz, Clara Marincowitz | This work is licensed under CC Attribution 4.0
Submitted: 28 April 2024 | Published: 05 August 2024

About the author(s)

Victoria Mashele, Department of Family Medicine, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa; and Health Limpopo, Mankweng Hospital, Polokwane, South Africa
Gert J.O. Marincowitz, Department of Family Medicine, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa; and Department of Family Medicine, Limpopo Department of Health, Mankweng Hospital, Polokwane, South Africa
Clara Marincowitz, Department of Psychiatry, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa; and SA Medical Research Council, Cape Town, South Africa

Abstract

Background: South Africa is among the countries with the greatest burden of human immunodeficiency virus (HIV) in the world. The introduction of antiretroviral therapy (ART) has made HIV a manageable chronic health condition with a return to normal life expectancy. Adherence to ART is a prerequisite to realising these benefits.

Methods: A qualitative study was conducted using individual semi-structured interviews to understand factors influencing adherence to ART among young adults. The study was conducted at three busy primary care clinics around Mankweng Hospital. Participants aged 18–35 years who had been on ART for more than a year were purposefully selected. Open-ended questions were used to explore factors that influence ART. Recorded interviews were transcribed verbatim and translated. The coded transcripts were thematically analysed.

Results: Eight major themes were identified to influence ART adherence among young adults: medication-related factors, healthcare system factors, attitudes of healthcare workers, economic factors, disclosure, acceptance, mobile phone reminders and family support.

Conclusion: Adherence to ART is a major problem in our communities, and people living with HIV are still finding it challenging to optimally adhere to their ART medication because of the identified factors that influence ART adherence. Family support is a significant factor that was identified to positively influence ART as it leads to disclosure and acceptance of HIV-positive status, better emotional well-being and subsequently improved ART adherence.

Contribution: This study underscores the importance of a family-oriented, patient-centred care approach in managing HIV and ART adherence.


Keywords

antiretroviral therapy; adherence; factors influencing; challenges to antiretroviral therapy

Sustainable Development Goal

Goal 3: Good health and well-being

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